Vitality/vaɪˈtæləti/ Definition 1 of 3Pro Tip 1/3Living Energy Use 'vitality' to emphasize an organism's health and energetic spirit, not just being alive. The puppy's vitality was evident as it played. Pro Tip 2/3Rejuvenation Context 'Regain vitality' is often used when someone recovers energy after being sick or tired. After a good night's sleep, she regained her vitality. Pro Tip 3/3Not Just Physical Vitality can also refer to the liveliness of ideas, conversations, or social interactions. Their debate was full of vitality and passion.