Wipe/waɪp/ Definition 1 of 5Pro Tip 1/3Physical Action Wipe involves a hand motion; moving a cloth across something often with some pressure. She had to wipe the mirror several times to remove the smudges. Pro Tip 2/3Cleaning Purpose Wipe is typically used for cleaning or drying a surface or object. Please wipe your feet on the mat before entering. Pro Tip 3/3Surface Contact Wipe implies direct contact with the surface being cleaned. He used a tissue to wipe the dust from the shelf.