Bless you Definition 1 of 3Pro Tip 1/3Sneeze Response Customarily said after sneezing to wish good health. Achoo! 'Bless you!' Pro Tip 2/3Not Religious While originating from superstition, it's used no matter the religion. He sneezed, and even in the office everyone said 'bless you.' Pro Tip 3/3Alternate 'Gesundheit' In some places, 'gesundheit' is used which means 'health' in German. 'Achoo!' 'Gesundheit!'