Change up Definition 1 of 3Pro Tip 1/3Casual Use The phrase 'change up' is informal, suitable for casual conversations. Maybe it's time to change up our weekend plans. Pro Tip 2/3Subtle Shift Indicates a minor or subtle modification rather than a complete overhaul. Let's change up the room's layout for a fresh look. Pro Tip 3/3Refreshing Change Often suggests a positive, refreshing variation from a regular pattern. We should change up our meal prep routine to add some excitement.