Often implies financial trouble or unprofitability, more than other reasons for stopping operations. Many shops close down if they're not making enough money.
Pro Tip 2/3
Employee Effects
Highlights the impact on employees who lose their jobs when their workplace closes down. After the factory closed down, many workers were unemployed.
Pro Tip 3/3
Permanent or Temporary
Can refer to a temporary situation or a business closing forever; context is key. The shop closed down for renovation but will reopen next month.