Fight off Definition 1 of 2Pro Tip 1/3Physical Defense Often relates to defending oneself from physical harm or attack from others. She managed to fight off the mugger and escaped unharmed. Pro Tip 2/3Action Intensity Conveys a sense of vigorous or intense action to prevent harm. During the match, he fought off several tackles to score a goal. Pro Tip 3/3Persistence Required Suggests a continued effort over time, not just a single moment. Survivors fought off the icy weather until the rescue team arrived.