This phrase is a harsh way to dismiss someone, showing irritation or anger towards them. When he tried to sell me something useless, I said 'get stuffed' and walked away.
Pro Tip 2/3
Informal Setting
Use this phrase only in casual situations among friends or peers where frankness is acceptable. After the joke went too far, I told my friend to get stuffed.
Pro Tip 3/3
Potentially Offensive
Be aware that some people may find this phrase offensive. Use it with caution and know your audience. She told the intrusive salesman to get stuffed, but she regretted her rudeness later.