Guard against Definition 1 of 3Pro Tip 1/3Negative Outcome Use 'guard against' when you want to prevent something unfavorable from occurring. It's wise to guard against cyber attacks by using strong passwords. Pro Tip 2/3Proactive Steps It implies taking early or cautionary steps to stop a bad thing before it starts. She installed an alarm system to guard against break-ins. Pro Tip 3/3Ongoing Vigilance The phrase suggests a continuous effort, not just a one-time action. They guard against plagiarism in every project they undertake.