Use when you're facing the same situation again, particularly an unwelcome one. My car broke down on the way to work. Here we go again!
Pro Tip 2/3
Sarcastic Tone
The phrase can be used with a touch of irony or sarcasm in response to repetitive actions. It's Monday and the boss is already yelling. Here we go again...
Pro Tip 3/3
Expectation of Trouble
Often implies a sense of resignation to recurring problems or hassles. The toddlers are painting the walls, not the paper. Here we go again!