In South Africa, 'hold thumbs' means the same as 'crossing fingers' and is a way to wish good luck. She's taking her driving test today, so I'm holding thumbs.
Pro Tip 2/3
Positive Support
'Hold thumbs' is used to show support and optimism towards someone's situation or outcome. We're holding thumbs that the weather stays clear for the picnic.
Pro Tip 3/3
Informal Use
The phrase is informal, so it's best used with friends, family, or casual settings, not in formal situations. Got a job interview? I'll hold thumbs for you!