In spite of yourself Definition 1 of 1Pro Tip 1/3Unplanned Reaction Refers to an automatic response you didn't anticipate, showing real feelings. Even though he was angry, he helped her, in spite of himself. Pro Tip 2/3Unexpected Enjoyment You might enjoy something you thought you wouldn't, surprising yourself. She found the silly movie amusing, in spite of herself. Pro Tip 3/3Reluctant Admission Acknowledging something positive that you are reluctant to accept. In spite of himself, he admitted that the critique was fair.