Infarction/ɪnˈfɑːrkʃn/ Definition 1 of 2Pro Tip 1/3Specific Damage Refers to tissue damage, often related to the heart, due to oxygen shortage. His lifestyle choices led to an infarction, requiring surgery. Pro Tip 2/3Severity Implication Indicates a serious health issue, usually demands immediate medical attention. The sudden infarction alarmed the paramedics. Pro Tip 3/3Heart Association Commonly paired with 'myocardial', it refers specifically to heart attacks. Myocardial infarction is the medical term for a heart attack.