While often about a lost chance, it can describe a missed misfortune, hence not entirely regrettable.

Not Always Negative

Used in casual conversations, might not be suitable for very formal writing.

Informal Context

Commonly used in business and personal contexts where seizing the moment is valued.

It's about failing to grasp the essence or underlying message of something.

Can express a social gaffe where someone's cluelessness is noticeable.

Use it to point out that someone didn't catch on to a topic or reference during discussions.