Over the counter Definition 1 of 3Pro Tip 1/3Common Medicines Refers to widely used drugs that don't require a prescription. Antacids are also available over the counter. Pro Tip 2/3No Prescription Highlights that these items can be bought directly, with no doctor's note. Can I get this medication over the counter or do I need a prescription? Pro Tip 3/3Immediate Purchase Implies you can buy it on the spot without waiting for approval. I bought ibuprofen over the counter at the nearest pharmacy.