Pick on Definition 1 of 2Pro Tip 1/3Power Dynamics Use 'pick on' when someone uses their strength or status to target someone weaker. The older kids tend to pick on the younger ones during recess. Pro Tip 2/3Negative Emotion 'Pick on' implies causing distress and is seen as negative behavior. Whenever there's a mistake, my boss picks on me instead of anyone else. Pro Tip 3/3Repeated Action 'Pick on' often suggests a habitual action, not a one-time event. Alex is always picking on his classmates for their accents.