Acclimatize/əˈklaɪmətaɪz/ Definition 1 of 3Pro Tip 1/3Personal Adjustment Implies a period of discomfort while getting used to new conditions. She had to acclimatize to living alone. Pro Tip 2/3Active Effort Suggests an active process to feel comfortable in new settings. He tried to acclimatize himself by taking daily walks outside. Pro Tip 3/3Change Over Time Indicates that acclimatization is gradual, not immediate. You'll acclimatize to the new school routine in time.