Actuate/ˈæktʃueɪt/ Definition 1 of 2Pro Tip 1/3Mechanical Context Actuate often relates to mechanical or electrical processes. An operator actuated the conveyor belt to start the packaging process. Pro Tip 2/3System Activation Actuate highlights the start of a system's operation rather than ongoing functioning. The floodgates were actuated to manage the rising water levels. Pro Tip 3/3Initiate Action Using 'actuate' implies direct initiation, often at the beginning of a process. To actuate the cleaning cycle, press the red button now.