Calcification/ˌkælsɪfɪˈkeɪʃn/ Definition 1 of 2Pro Tip 1/3Health Concern Calcification in a medical context often indicates potential health issues. Regular check-ups can detect early calcification in joints. Pro Tip 2/3Technical Term Used mainly in scientific or medical discussions among professionals. The patient showed extensive calcification in the hip area. Pro Tip 3/3Negative Implication The word often implies a negative change in tissue or vessels. His X-ray revealed calcification where flexibility is essential.