Use 'doubtless' to stress a very high degree of certainty or likelihood about something. Doubtless, the sun will rise again tomorrow.
Pro Tip 2/3
Predictive Context
It's often used when predicting something that seems sure to happen or when it's a foregone conclusion. Doubtless, the team's victory will be celebrated long into the night.
Pro Tip 3/3
Formal Tone
'Doubtless' is formal and fits best in official or literary contexts rather than casual conversation. Doubtless, this discovery will alter the course of our research.