Ese/iz, is/ Definition 1 of 5Pro Tip 1/3Friendly Address Use 'ese' between close friends or peers, similar to 'dude' or 'bro'. Thanks for the help, ese! Pro Tip 2/3Cultural Identity 'Ese' signifies belonging or identity among Mexican Americans, conveys camaraderie. Ese, let's celebrate our heritage together. Pro Tip 3/3Context Specific 'Ese' is casual and may be inappropriate in formal or professional settings. You wouldn't say 'ese' to your boss.