Esophagus/iˈsɑːfəɡəs/ Definition 1 of 1Pro Tip 1/3Human Anatomy Belongs to human anatomy vocabulary; important for discussing health issues. The doctor explained the role of the esophagus in digestion. Pro Tip 2/3Medical Context Often used in medical or healthcare settings; less common in everyday conversation. The patient's esophagus was inflamed due to acid reflux. Pro Tip 3/3Disease Association Can be associated with various diseases, making it a serious term when used. My aunt was diagnosed with esophagus cancer last year.