Heartsick
/ˈhɑːrtsɪk/
Definition 1 of 1
Pro Tip 1/3Deep Sadness
Use 'heartsick' to express a profound feeling of sadness that is often hard to overcome. 
He felt heartsick when he learned about the tragedy.
Pro Tip 2/3Emotional Upset
'Heartsick' implies a level of emotional pain that affects one's whole state of being, not just the mind. 
After the breakup, she was heartsick for weeks.
Pro Tip 3/3Not Physical
'Heartsick' does not refer to a physical illness, but rather an emotional condition. 
Despite being in good health, he was heartsick over his lost love.